The parts that first suffer from alcohol are those expansions of the body which the anatomists call the membranes. “The skin may be a membranous envelope. Through the whole of the alimentary surface, from the lips downward, and thru the bronchial passages to their minutest ramifications, extends the mucous membrane. The lungs, the guts, the liver, the kidneys are folded in delicate membranes, which can be stripped easily from these parts. If you are taking a little of bone, you will notice it easy to strip far from it a membranous sheath or covering; if you examine a joint, you’ll find both the pinnacle and also the socket lined with membranes. The full of the intestines are enveloped in a very fine membrane known as  peritoneum . All the muscles are enveloped in membranes, and the fasciculi, or bundles and fibres of muscles, have their membranous sheathing. The brain and spinal twine are enveloped in three membranes; one nearest to themselves, a pure vascular structure, a network of blood-vessels; another, a thin serous structure; a 3rd, a strong fibrous structure. The eyeball is a structure of colloidal humors and membranes, and of nothing else. To finish the outline, the minute structures of the important organs are enrolled in membranous matter.”

These membranes are the filters of the body. “In their absence there could be no building of structure, no solidification of tissue, nor organic mechanism. Passive themselves, they, nevertheless, separate all structures into their respective positions and adaptations.”

Membranous deteriorations.
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In order to make perfectly clear to your mind the action and use of those membranous expansions, and the manner in which alcohol deteriorates them, and obstructs their work, we quote once more from Dr. Richardson:

“The animal receives from the vegetable world and from the planet the foods and drinks it needs for its sustenance and motion. It receives colloidal food for its muscles: combustible food for its motion; water for the answer of its various parts; salt for constructive and other physical purposes. These have all to be organized in the body; and they are organized by means of the membranous envelopes. Through these membranes nothing can pass that’s not, for the time, during a state of aqueous solution, like water or soluble salts. Water passes freely through them, salts pass freely through them, however the constructive matter of the active components that is colloidal does not pass; it’s retained in them until it’s chemically decomposed into the soluble kind of matter. Once we take for our food a little of animal flesh, it is initial resolved, in digestion, into a soluble fluid before it can be absorbed; in the blood it is resolved into the fluid colloidal condition; within the solids it’s laid down inside the membranes into new structure, and when it has played its half, it is digested once more, if I could therefore say, into a crystalloidal soluble substance, ready to be frenzied and replaced by addition of new matter, then it’s dialysed or more matured, the membranes into the blood, and is disposed of in the excretions.

“See, then, what an all-important half these membranous structures play within the animal life. Upon their integrity all the silent work of the building up of the body depends. If these membranes are rendered too porous, and unchained the colloidal fluids of the blood the albumen, for instance the body so circumstanced, dies; dies as if it were slowly bled to death. If, on the contrary, they become condensed or thickened, or loaded with foreign material, then they fail to permit the natural fluids to go through them. They fail to dialyse, and the result’s, either an accumulation of the fluid in an exceedingly closed cavity, or contraction of the substance inclosed within the membrane, or dryness of membrane in surfaces that must be freely lubricated and kept apart. In old age we see the effects of modification of membrane naturally induced; we see the fastened joint, the shrunken and feeble muscle, the dimmed eye, the deaf ear, the enfeebled nervous function.

“It could probably appear, at 1st sight, that I am leading immediately away from the subject of the secondary action of alcohol. It’s not so. I’m leading on to it. Upon all these membranous structures alcohol exerts a direct perversion of action. It produces in them a thickening, a shrinking and an inactivity that reduces their useful power. That they may work rapidly and equally, they require to be in any respect times charged with water to saturation. If, into contact with them, any agent is brought that deprives them of water, then is their work interfered with; they cease to separate the saline constituents properly; and, if the evil that is therefore started, be allowed to continue, they contract upon their contained matter in whatever organ it may be situated, and condense it.

“Briefly, beneath the prolonged influence of alcohol those changes which happen from it within the blood corpuscles, extend to the opposite organic components, involving them in structural deteriorations, that are continually dangerous, and are usually ultimately fatal.”

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